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Consulta la bibliografia.

Pagina “Osteoartrosi”  
[1] Revisione a cura del Registro italiano ArtroProtesi – Riap, Istituto superiore di sanità – Iss.[2] Osteoarthritis in 2020 and beyond: a Lancet Commission. David J Hunter, Lyn March, Mabel Chew. VOLUME 396, ISSUE 10264, P1711-1712, NOVEMBER 28, 2020.[3] State of the evidence. Allen KD, Golightly YM. Curr Opin Rheumatol. 2015;27(3):276.
[4] A meta-analysis of sex differences prevalence, incidence and severity of osteoarthritis. Srikanth VK, Fryer JL, Zhai G, Winzenberg TM, Hosmer D, Jones G. Osteoarthritis Cartilage. 2005;13(9):769.
[5] Genetic association studies in osteoarthritis: is it fairytale? Warner SC, Valdes AM . Curr Opin Rheumatol. 2017;29(1):103.
[6] Risk factors and burden of osteoarthritis. Palazzo C, Nguyen C, Lefevre-Colau MM, Rannou F, Poiraudeau S. Ann Phys Rehabil Med. 2016;59(3):134. Epub 2016 Feb 19.
[7] The influence of alignment on risk of knee osteoarthritis progression according to baseline stage of disease. Cerejo R, Dunlop DD, Cahue S, Channin D, Song J, Sharma L. Arthritis Rheum. 2002;46(10):2632.
[8] Osteoarthritis, obesity and weight loss: evidence, hypotheses and horizons – a scoping review. Bliddal H, Leeds AR, Christensen R. Obes Rev. 2014;15(7):578. Epub 2014 Apr 22.

[9] Exercise for knee osteoarthritis. Baker K, McAlindon T. Curr Opin Rheumatol. 2000;12(5):456.
[10] The association between smoking and knee osteoarthritis in a cohort of Danish patients undergoing knee arthroscopy. Johnsen MB, Pihl K, Nissen N, Sørensen RR, Jørgensen U, Englund M, Thorlund JB. BMC Musculoskelet Disord. 2019;20(1):141. Epub 2019 Apr 1.

[11] Regenerative approaches for cartilage repair in the treatment of osteoarthritis. M.H. Li, R. Xiao, J.B. Li, Q. Zhu. OCTOBER 2017, 25(10): P1577-1587.
Pagina “Traumatologia dello Sport” 
[1] Overview of Injuries in the Young Athlete. Terry A. Adirim1 and Tina L. Cheng2 Sports Med 2003; 33 (1): 75-81.
Pagina “Medicina Rigenerativa” 
[1] Neogi T, Zhang Y. Epidemiology of osteoarthritis. Rheum Dis Clin N Am 2013; 39(1):1-19.
[2] Sokolove J, Lepus CM. Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretations. Therapeut Adv Musculoskel Dis 2013; 5(2):77-94.
[3] Baer PC, Geiger H. Adipose-derived mesenchymal stromal/ stem cells: tissue localization, characterization, and hetero- geneity. Stem Cell Int 2012;2012:812693.
[4] Pak J, Lee JH, Park KS, Park M, Kang LW, Lee SH. Current use of autologous adipose tissue-derived stromal vascular fraction cells for orthopedic applications. J Biomed Sci 2017 Jan 31;24(1):9.
[5] Bourin et al. Position Statement. Stromal cells from the adipose tissue-derived stromal vascular fraction and culture expanded adipose tissue-derived stromal/stem cells: a joint statement of the International Federation for Adipose Therapeutics and Science (IFATS) and the International Society for Cellular Therapy (ISCT). Cytotherapy, 2013; 15:641-648.
[6] Varghese J, Griffin M, Mosahebi A, Butler P. Systematic review of patient factors affecting adipose stem cell viability and function: implications for regenerative therapy. Stem Cell Res Ther. 2017; 8(1):45.
[7] V. Van Harmelen, T. Skurk, K. Ro ̈hrig et al., “Effect of BMI and age on adipose tissue cellularity and differentiation capa- city in women,” International Journal of Obesity, vol. 27, no. 8, pp. 889–895, 2003.
[8] Zhang S. et al. MSC exosomes mediate cartilage repair by enhancing proliferation, attenuating apoptosis and modulating immune reactivity. Biomaterials 2018; 156:16-27.
[9] Liu T.M. et al. Identification of common pathways mediating differentiation of bone marrow- and adipose tissue-derived human mesenchymal stem cells into three mesenchymal lineages. STEM CELLS 2007; 25:750 –760 .
[10] McAlindon TE, Bannuru RR, Sullivan MC, et al. OARSI guidelines for the non-surgical management of knee osteoarthritis. Osteoarthritis Cartilage 2014; 22: 363–88.
[11] Bartholdy C. et al. The role of muscle strengthening in exercise therapy for knee osteoarthritis: A systematic review and meta-regression analysis of randomized trials. Seminars and Arthritis and Rheumatism 2017; 47:9-21.
[12] Tamás J. et al. Mechanical loading stimulates chondrogenesis via the PKA/CREB-Sox9 and PP2A pathways in chicken micromass cultures. Cellular Signalling 2014; 26 (13):468-482.
Pagina “Terapia Rigenerativa” 
[1] Two-year clinical outcomes of autologous microfragmented adipose tissue in elderly patients with knee osteoarthritis: a multi-centric, international study. GOBBI A. et al. International Orthopaedics, March 2021.
[2] Functional outcomes following microfragmented adipose tissue versus bone marrow aspirate concentrate injections for symptomatic knee osteoarthritis. MAUTNER, K., et al. Stem cells translational medicine, 2019, 8.11: 1149-1156.
[3] Adipose Tissue and Mesenchymal Stem Cells: State of the Art and Lipogems® Technology Development. Carlo Tremolada, Valeria Colombo, Carlo Ventura. Curr Stem Cell Rep (2016) 2:304-312.
[4] Comprehensive Review of Knee Osteoarthritis Pharmacological Treatment and the Latest Professional Societies’ Guidelines. PRIMORAC et al. Pharmaceuticals 2021, 14, 205.
[5] Microfragmented adipose injections in the treatment of knee osteoarthritis. MALANGA, G. A., et al. Journal of Clinical Orthopaedics & Trauma, 2019, 10.1: 46-48.